I started reading There There by Tommy Orange and in the introduction I was introduced to an alternate version of Thanksgiving.  In this one, the native Americans / Indians are slaughtered by European colonists just a few years after their arrival.

To be sure my memory, and perhaps education, on this subject is a bit confused.  I seem to have mixed the Pilgrims, the Puritans and the Virginia Commonwealth settlers.  They all arrived around the same time, and seem to have gone through the same quick cycle with the locals.  Of course, the English had arrived in the middle of ongoing tribal conflicts.  Being both naive and heavily armed all but guaranteed conflict with the natives.

Indian massacre of 1622